Temperature‐corrected proton density fat fraction estimation using chemical shift‐encoded MRI in phantoms
نویسندگان
چکیده
Purpose Chemical shift‐encoded MRI (CSE‐MRI) is well‐established to quantify proton density fat fraction (PDFF) as a quantitative biomarker of hepatic steatosis. However, temperature known bias PDFF estimation in phantom studies. In this study, strategies were developed and evaluated correct for the effects on through simulations, temperature‐controlled experiments, multi‐center, multi‐vendor study. Theory Methods A technical solution that assumes automatically estimates uniform, global throughout proposed. Computer simulations modeled effect using magnitude‐, complex‐, hybrid‐based CSE‐MRI methods. Phantom experiments performed assess correction at controlled temperatures. To method larger scale, proposed was applied data acquired part nine‐site study compared temperature‐corrected an priori guess ambient room temperature. Results Simulations show deviates further from assumed temperature, increases. Using reasonable variability reduced magnitude‐based CSE‐MRI, across systems, field strengths, protocols, varying Complex hybrid methods showed little both before after correction. Conclusion Correction reduces temperature‐related phantoms vendors, sites, protocols even without information about
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ژورنال
عنوان ژورنال: Magnetic Resonance in Medicine
سال: 2021
ISSN: ['0740-3194', '1522-2594']
DOI: https://doi.org/10.1002/mrm.28669